Job No. 155922
- Job Title:
- Research Lab Specialist Senior
- Employer:
-
University of Michigan-Ann Arbor
- Location:
-
Ann Arbor , MI
- Posting Date:
- 18-Jul-2025
- Description:
-
Job Summary
The microbiome represents an exciting frontier in medicine, and early successes in the field have demonstrated the dynamic interactions among individual microbial species and highlighted the crosstalk between microbiota and their hosts at the mucosal interface. The Li research group has been focusing on the development of molecular and live cell-based therapeutics, with a major emphasis on harnessing innovative synthetic biology, microbial engineering, and drug delivery approaches for improving human health in a sustainable manner. Currently, three directions are being explored: (1) engineering probiotics to secrete biologics such as nanobodies to address intestinal diseases; (2) understanding the interactions between oral microbiota and the host; and (3) engineering probiotics for cancer immunotherapy.
The Li Lab, now at the University of Michigan, develops innovative molecular and live cell-based therapeutics through synthetic biology, microbial engineering, and drug delivery. Research areas include engineering probiotics for intestinal diseases and cancer immunotherapy and studying oral microbiota-host interactions. The lab is supported by both internal and extramural funding sources.
Mission Statement
Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.
Why Join Michigan Medicine?
Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.
What Benefits can you Look Forward to?
Excellent medical, dental and vision coverage effective on your very first day
2:1 Match on retirement savings
Responsibilities*
Communicate with vendors on purchasing instruments.
Facilitate day-to-day research laboratory operations, including procurement and inventory of reagents and supplies.
Manage the laboratory's IBC protocol to ensure safe usage of recombinant DNA constructs, viral gene delivery systems, and human cell cultures.
Manage multiple IACUC protocols (involving rodents) and serve as the point of contact for biannual IACUC inspections.
Serve as the laboratory's safety officer, maintaining all required documentation for annual EHS inspections.
Provide technical support to a range of research projects using various techniques including bacterial and mammalian cell culture, recombinant DNA techniques, and qPCR.
Facilitate animal research by the faculty, students, and postdocs in the lab by assisting with animal surgeries and post-surgical care.
Required Qualifications*
Master's degree or PhD, preferably in microbiology, molecular biology, bioengineering, chemistry, or related discipline.
5-6 years related experience.
Candidates must be interested in working with technical aspects of cancer/rare disease diagnosis/therapy and their translations to clinical applications.
Familiar with the operation and performance of basic lab equipment, i.e., centrifuge, microscopes, etc.
Good organizational skills and ability to work alongside other scientists without extensive supervision.
Willingness to learn new techniques as required for project progress.
Desired Qualifications*
Familiarity with molecular cloning, flow cytometry, immunoassays, cell and organoid culture is preferred.
Experience of animal models is strongly preferred.
- Contact information:
- University of Michigan-Ann Arbor
- Ann Arbor, MI 48109
- United States
- Employer's Website:
-
Visit Employer's website